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E2f5

Official Full Name
E2F transcription factor 5, p130-binding
Background
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms.
Synonyms
E2F5; E2F transcription factor 5, p130-binding; transcription factor E2F5; E2F 5; E2F transcription factor 5; E2F transcription factor 5 p130 binding; p130 binding; OTTHUMP00000227505; OTTHUMP00000227506; OTTHUMP00000227507; OTTHUMP00000227508; E2F-5; E2F4; cb735; zgc:111879

Cat.No. Product Name Price
SHH021899shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021900shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021901shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021902shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021903shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021904shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021905shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021906shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021907shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021908shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021913shRNA set against Human E2F5(NM_001951.3)Inquiry
SHH021915shRNA set against Mouse E2f5(NM_007892.2)Inquiry
SHH021933shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021938shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021939shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021940shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021941shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021942shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021943shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021944shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021945shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021946shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021947shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021948shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021949shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021950shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021951shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021952shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021953shRNA set against Human E2F5(NM_001083589.1)Inquiry
SHH021954shRNA set against Human E2F5(NM_001083588.1)Inquiry
SHH021955shRNA set against Human E2F5(NM_001951.3)Inquiry
SHH282529shRNA set against Human E2F5 (NM_001951.3)Inquiry
SHH282533shRNA set against Mouse E2F5 (NM_007892.2)Inquiry
SHW001573shRNA set against Chicken E2F5 (NM_001030942)Inquiry
SHW013712shRNA set against Danio rerio E2F5 (NM_001197300)Inquiry
SHW017537shRNA set against Danio rerio E2F5 (NM_205615)Inquiry

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