Official Full Name

carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

Background

Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix;and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in;which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts;as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been;identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling;receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Synonyms

CHST15; carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15; carbohydrate sulfotransferase 15; B cell RAG associated protein; BRAG; GALNAC4S 6ST; KIAA0598; N acetylgalactosamine 4 sulfate 6 O sulfotransferase; hBRAG; B-cell RAG-associat; GALNAC4S-6ST; RP11-47G11.1; KIAA0598, MGC34346, RP11-47G11.1, DKFZp781H1369