C-C motif chemokine receptor 3

Home
Products
Services
Applications
CDMO
AI
Support
About Us
- Corporate
- Careers
- Events
- Contact Us
- Order Online

Inquiry

Pages

Products

CCR3

Official Full Name

C-C motif chemokine receptor 3

Organism

Homo sapiens

GeneID

1232

Background

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]

Synonyms

CKR3; CD193; CKR 3; CMKBR3; C C CKR3; CC-CKR-3;

Bio Chemical Class

GPCR rhodopsin

Protein Sequence

MTTSLDTVETFGTTSYYDDVGLLCEKADTRALMAQFVPPLYSLVFTVGLLGNVVVVMILIKYRRLRIMTNIYLLNLAISDLLFLVTLPFWIHYVRGHNWVFGHGMCKLLSGFYHTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIVTWGLAVLAALPEFIFYETEELFEETLCSALYPEDTVYSWRHFHTLRMTIFCLVLPLLVMAICYTGIIKTLLRCPSKKKYKAIRLIFVIMAVFFIFWTPYNVAILLSSYQSILFGNDCERSKHLDLVMLVTEVIAYSHCCMNPVIYAFVGERFRKYLRHFFHRHLLMHLGRYIPFLPSEKLERTSSVSPSTAEPELSIVF

Open

Disease

Asthma, Parkinsonism, Vasomotor/allergic rhinitis

Approved Drug

Clinical Trial Drug

4 +

Discontinued Drug

3 +

Cat.No.	Product Name	Price
CSC-DC002673	Panoply™ Human CCR3 Knockdown Stable Cell Line	Inquiry
CSC-RG1140	Human CCR3 Stable Cell Line-K562	Inquiry
CSC-SC002673	Panoply™ Human CCR3 Over-expressing Stable Cell Line	Inquiry

Cat.No.	Product Name	Price
CSC-DC002673	Panoply™ Human CCR3 Knockdown Stable Cell Line	Inquiry
CSC-RG1140	Human CCR3 Stable Cell Line-K562	Inquiry
CSC-SC002673	Panoply™ Human CCR3 Over-expressing Stable Cell Line	Inquiry

Cat.No.	Product Name	Price
CSC-DC002673	Panoply™ Human CCR3 Knockdown Stable Cell Line	Inquiry
CSC-RG1140	Human CCR3 Stable Cell Line-K562	Inquiry
CSC-SC002673	Panoply™ Human CCR3 Over-expressing Stable Cell Line	Inquiry

Cat.No.	Product Name	Price
CSC-DC002673	Panoply™ Human CCR3 Knockdown Stable Cell Line	Inquiry
CSC-RG1140	Human CCR3 Stable Cell Line-K562	Inquiry
CSC-SC002673	Panoply™ Human CCR3 Over-expressing Stable Cell Line	Inquiry

Quick Inquiry

Receive a quote or more information about stable cell line generation services.

If you don’t find the cell line you want, Creative Biogene can also provide stable cell line generation service with the best prices and fastest turnaround time for you! Contact us for more information or to request a quote.

Request a quote today!

Inquiry

We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy