Luciferase Reporter Cell Line - MC38

MC38 is a mouse colon adenocarcinoma cell line originally derived from colon tumors induced by the chemical carcinogen azomethane in C57BL/6 mice. These cells have been widely used as a model system to study various aspects of colon cancer biology, including the molecular mechanisms of tumor initiation and progression, and to identify potential therapeutic targets for colon cancer treatment. MC38 cells have a variety of properties. First, they are relatively easy to cultivate in the laboratory and can be grown in large quantities. Second, they express markers of colon cancer, such as carcinoembryonic antigen (CEA) and cytokeratin, and exhibit some characteristics of colon cancer, including uncontrolled proliferation, invasion, and metastasis. Third, they respond to various stimuli, such as cytokines and growth factors, making them useful model systems to study the effects of these factors on colon cancer cell growth and survival. Luciferase Reporter Cell Line - MC38 is a genetically engineered variant of the widely studied MC38 murine colon cancer cell line. In this enhanced cell line, cells are used to express the gene for luciferase, a bioluminescent protein originally derived from fireflies. With this modification, cells are able to produce light in response to certain stimuli, which can then be measured using bioluminescence imaging techniques. This property makes the luciferase reporter cell line - MC38 an important tool for a variety of biomedical research, including studies of cancer progression, cellular immune responses, and the effectiveness of potential new drugs.