Cas9 Stable Cell Line - HepG2

Cas9 stable cell line-HepG2 has multiple applications in various fields of scientific research, especially in the fields of genomics and molecular biology. From perspective, here are some applications: Gene editing: The main application of Cas9 Stable Cell Line-HepG2 is CRISPR-CAS9-mediated gene editing. The researchers used the tool to introduce or delete specific DNA sequences in the genome of HepG2 cells. This advanced technology allows scientists to study gene function and genetic variation. Targeted gene knockout: Cell lines generate in vitro models by knocking out specific target genes. This aids scientific research by helping to understand disease mechanisms and for use in drug development studies. Functional genomics: The Cas9 stable cell line-HepG2 is also used for functional genomics studies. With the ability to edit any gene, scientists can unlock and evaluate the performance of individual genes in the genome. Disease modeling: Given that HepG2 is originally derived from human liver cancer cells, this cell line is used for human disease modeling, particularly liver-related diseases. By introducing specific genetic alterations, researchers can create disease models to study pathology and potential treatments. Drug screening: Cas9 stable cell line-HepG2 is an excellent platform for drug screening and toxicology research. Given their genetic modification capabilities, these cells can be used to study drug efficacy and potential toxicity.