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The release of the Cas12a (also known as Cpf1) system in 2015 aroused widespread interest from researchers. As one of the DNA cutting proteins, CRISPR/Cas12a is complementary to Cas9 with several advantages.
The extended PAM sequence, staggered cutting pattern and simplified crRNA structure make Cas12a an ideal enzyme for simple, fast, and accurate disease diagnosis.
Figure 1: The mechanism of CRISPR/Cas12a (Zhiliang Yang. 2019)
CRISPR/Cas9 PlatformCB, a global biotechnology company, provides comprehensive CRISPR/Cas12a products and services for genomics and proteomics researchers to promote the development of basic biological research, human disease research, and drug discovery.
Our CRISPR/Cas12a genome editing services include, but are not limited
Based on the gene ID you provided, we will screen at least three PAM (TTTN) sites and synthesize your crRNA sequence using chemical modification method to improve the stability of crRNA in target cells and further improve target editing performance.
➢ All crRNAs contain a 21 base protospacer for optimal activity.
➢ Provide negative control crRNA, non-targeted in human, mouse and rat genomes (optional).
➢ We offer multiple vector designs including crRNA only, crRNA-Cas12a.
➢ TET inducible or stable expressed CRISPR/Cas12a construct.
➢ Multiple vectors including non-viral and viral vectors (lentivirus, adenovirus, AVV).
➢ Viral vectors have the ability to transfect a variety of cells, including cells that are difficult to transfect, such as stem cells, primary cells, suspension cells, etc.
CRISP/Cas9 PlatformCB generates your crRNA sequence or CRISP/Cas12a vector at the best quality and best price. Our unique technology ensures fast turnaround times. In addition, we provide Cas12a (Cpf1) protein purified from E. coli and pcDNA3.1-hLbCpf1 vectors. We guarantee high-quality products and services to meet your different needs. There is no doubt, CRISP/Cas9 PlatformCB is the best partner during your research.
CRISPR/Cas12a related products
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