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CRISPR is a useful tool for gene screening experiments because it is relatively easy to design gRNA and has the ability to modify almost any gene locus. In CRISPR screening experiments, target cells are treated with a screening library to generate a population of mutant cells, which are then screened for the phenotype of interest. For example, the CRISPR library can detect drug-treated cells. Positive selection can easily elucidate drug resistance mechanisms. Negative selection can effectively detect dead cells or slow-growing cells, helping researchers identify genes and proteins that cause or prevent disease, thereby identifying potential drug targets.
CRISPR/Cas9 PlatformCB is committed to providing researchers with convenient, fast and reliable genetic editing products to facilitate the application of the CRISPR system to your projects in a simple way. We offer a wide range of gRNA libraries covering human and mouse, all of which contain pre-validated sequences, including whole-genome lentivirus libraries for human and mouse whole-genome knockouts. We guarantee the high quality of our products designed and completed by our team of genetic editing experts.
If you do not find the product you interest in in the product list below, please do not hesitate to contact us. We also provide you with custom-made CRISPR/Cas9 screening library construction service, you only need to tell us your purpose.