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The development of next-generation sequencing technology has greatly promoted the development of precision medicine and personalized medicine. By sequencing, researchers can compare mutations in a gene more directly between different cells. However, there are often many other mixed characteristics that mask the direct relationship between genotype and disease.
With the maturity and universal application of the CRISPR/Cas9 system, researchers will be able to edit target genes in living cells and accurately change the DNA sequence, laying a foundation for developing new therapies for human diseases.
CRISPR/Cas9 PlatformCB can provide professional sgRNA bioinformatics data analysis services according to the specific needs of customers, covering sgRNA design, synthesis, and gene editing. By combining PREEGOC, TEGA, COSMIC and other professional databases, we can analyze and screen gene expression information, gene mutation frequency information, and post-clinical correlation data, and conduct integrated biological genomics analysis to provide potential drug targets and personalized medicine solution. At the same time, it can also help researchers find other additional genes that can be used as therapeutic targets.
➢ gRNA design
➢ High throughput gene synthesis
➢ Vectors construction
➢ NGS validation
➢ Virus packaging
➢ Stable plant construction
➢ Positive control test - Drug resistance test
➢ Negative controlled trials - Reporter testing
➢ Genetic structure analysis
➢ Unigene annotation
➢ Functional annotation and enrichment analysis of differential genes
Our characteristics and advantages
Next-generation sequencing in gene editing
|CRISPR/Cas9 gene editing||Next-generation sequencing enablement|
|Select gRNA target sites||Genome/gene/loci resequencing|
|CRISPR system delivery||Plasmid resequencing|
|Verification||High resolution on- and off-target assessment|
|Functional confirmation||RNA-Seq, single-cell RNA-Seq, Chip-Seq, etc.|
Our work is based on our knowledge and understanding of the CRISPR system and its applications. More importantly: we are experts in CRISPR gene-editing technology. We guarantee or clients high-quality services and products. If you have any questions or requirements, don't hesitate to contact us.