Other CRISPR-Related Editing Services    

The discovery, characterization, and development of the CRISPR/Cas system is an important starting point for molecular biology in the 21st century. The potential of developing easier-to-use variants of these systems promises to open many doors for genetic engineering in the fields of genome editing and non-genome editing.

CRISPR/Cas9 Platform^CB is experienced in providing a wide range of CRISPR system development services. Based on our in-depth expertise in CRISPR systems and years of CRISPR system application experience, we established a support platform for potential applications of the CRISPR system. Our service expertise covers the latest Cas12 and Cas13. Our researchers follow strict quality control standards and comprehensively optimize and verify all aspects of the project.

Project includes

• Cas12 target site screening

Cas12 is considered to be a more accurate DNA nuclease than Cas9, suitable for GC-rich genomes. We will select the most suitable PAM (TTTN) site for you based on the gene ID you provided.

• Cas12 crRNA design and synthesis

Design and synthesize at least three different crRNAs based on target sites

• Cas13 crRNA design and synthesis

Cas13 is a different endonuclease from Cas9, which can target single-stranded RNA. We will design and synthesize at least three types of pre-crRNA based on the gene ID you provided.

• dCas13 fusion protein construction
• CRISPR vector construction

➢ We offer different combinations of CRISPR vectors, including crRNA, crRNA-Cas12, crRNA-Cas13, etc.
➢ Different vector types (viral and non-viral)
➢ With fluorescent protein tag and screening gene

You only need to provide

• Species
• NCBI gene ID or gene symbol

Delivery

• 2-5 μg lyophilized plasmids containing sequence verified synthetic construct
• Sequence alignment data and alignment
• Separate synthetic gene sequences and sequence files in a vector library

Applications

• CRISPR/Cas12 is suitable for GC-rich genomic editing
• CRISPR/Cas13 system is suitable for target RNA editing and RNA living imaging
• Gene therapy research
• Study the function of genes/proteins

CRISPR/Cas9 Platform^CB is a global biotechnology company that provides products and services to genomics researchers in a wide range of markets including basic market research, biomarker discovery, human disease research and drug discovery. From experimental design to the application of the CRISPR system, we have found a solution to solve every step to help our customers carry out scientific research projects. We will assign dedicated project managers to each project to interact with clients to meet your specific requirements.