Key Targeted Gene Editing

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Key Targeted Gene Editing    

CRISPR/Cas9 gene editing technology brings a DNA editing revolution, which is faster, more accurate, less cost and has a wide range of potential applications than previous DNA editing techniques. Geneticists and medical researchers can use CRISPR/Cas9 technology to quickly delete, insert, or alter a portion of a DNA sequence. Guided by gRNA, Cas9 targets specific sites in the DNA and forms a double-stranded break (DSB). During DSB repair, one or more genetic changes are introduced through the non-homologous end joining (NHEJ) or homology directed repair (HDR, repair template required) pathway.

CRISPR PlatformCB, one of the leading gene editing technology companies, is specializing in CRISPR/Cas9 gene editing services. Based on our professional scientists' team and national-class labs, we have been successfully implemented hundreds of genes deletion in cells and mice using CRISPR/Cas9 technology (Table 1). We use optimized gene targeting strategies to achieve the most efficient gene editing efficiency, and we provide you with one-stop gene editing services, including designing gene editing strategies for the final cell line or model animal. To meet your research needs, we offer CRISPR/cas9 knockout, knock-in, point mutation, conditional knockout cell lines and animal models, etc.

Key Targeted Gene

ABCA1CCR4CLUFGF2IL-13RA2MSl1SMO
ABCC1CCR5CRBNFGF21IL-2mTORSOD1
ABCC3CD160CSF1RFGFR1IL-2RANOS2Src
ABL1CD19CSKFGFR2IL-3RANotch2SST
ACE2CD22CTCFLFGFR3IL-4Notch3STAT3
ADACD248CTGFFGFR4IL-4RNOX3STAT6
AhRCD27CTLA-4FLT1IL-6PARP1Syk
AKT1CD276CXCR1FLT3IL-6RPARP2TAT
AKT2CD28CXCR2FOXC2IL-8PARP3TBK1
AKT3CD33CXCR3FSHRIL-9RPCNATERT
ALDH2CD37CXCR4FynIRAK4PD1TF
ALKCD3eCXCR7GAS-6ITKPDE10ATGFB1
ApoBCD4CYP17A1GDF-2JAK1PDK1TLR3
ApoECD40CYP19A1GHRJAK2PECAM-1TLR4
ARCD44CYP2A6GLP1RJAK3PIGFTLR5
ARL-1CD47DDR1GLSKAAG1Pim1TLR7
ARVCFCD52DDR2GnRH1KIR-2DL1Pim2TLR8
ATF-5CD70DHFRGnRH-RKIR-2DL2Pim3TLR9
ATMCD74DHODHGPRC5DKIR-2DL3PKMTNIK
ATRAIDCD79BDKK1GRB2KIR-3DL2PLK-1TP53
AXLCD80DLL1GRP-RLAG-3PollTRPA1
Bcl2CD86DLL3GSTP1LCKPRAMETrpC5
Bcl-2A1CD9DLL4GZMBLDLRPRF1TrpV1
BcrCDC7DNMT1HDAC1LRRK2PRLTRPV2
BrafCDK1eEF1A-2HDAC2Ly-75PRL-RTSH-R
BMP-10CDK2EGFHDAC3LYNPRMT5Tyk2
BMXCDK3EGFRHDAC6MAP3K9PROX-1UCH-L5
Brd2CDK4ENGHDAC10MARCKSPTENUSP14
Brd3CDK5Ep-CAMHDAC11MC1-RPTK7VCAM-1
Brd4CDK6EphA2HGFMCL1RAD51VCP
BTKCDK7EphA3HIF1AMDM2RanVDR
CACDK8EphB4HK2Mdm4RETVIP
CA2CDK9EphB6HPSEMECOMROBO4Wee1/2
CA3CDK12ERBB2HSF1MELKROR1WNT5A
cAMPCDK19EZH2HSPB1MerTKSEMA-4DWT1
CCKA-RCEACAM5FASIGF1METSHEXIAP
CCKB-RCEBPAFASLGIGF1RMGMTSLAMF7 
CCR2CFTRFGF1IGF2MIFSLC6A8 

If you don't see the gene you are interested, please don't hesitate to contact us. CRISPR PlatformCB will provide you customized CRISPR/Cas9 gene editing services for your target genes. Tell us about your needs, we guarantee our clients the most reliable and efficient services to best match your research goals, with the shortest turnaround time and the most reasonable price.

For research use only. Not intended for any clinical use.

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