Key Targeted Gene Editing

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Key Targeted Gene Editing    

CRISPR/Cas9 gene editing technology brings a DNA editing revolution, which is faster, more accurate, less cost and has a wide range of potential applications than previous DNA editing techniques. Geneticists and medical researchers can use CRISPR/Cas9 technology to quickly delete, insert, or alter a portion of a DNA sequence. Guided by gRNA, Cas9 targets specific sites in the DNA and forms a double-stranded break (DSB). During DSB repair, one or more genetic changes are introduced through the non-homologous end joining (NHEJ) or homology directed repair (HDR, repair template required) pathway.

CRISPR PlatformCB, one of the leading gene editing technology companies, is specializing in CRISPR/Cas9 gene editing services. Based on our professional scientists' team and national-class labs, we have been successfully implemented hundreds of genes deletion in cells and mice using CRISPR/Cas9 technology (Table 1). We use optimized gene targeting strategies to achieve the most efficient gene editing efficiency, and we provide you with one-stop gene editing services, including designing gene editing strategies for the final cell line or model animal. To meet your research needs, we offer CRISPR/cas9 knockout, knock-in, point mutation, conditional knockout cell lines and animal models, etc.

Key Targeted Gene

ABCA1CCR4CLUFASNIGF1RMGMTSLAMF7
ABCC1CCR5CRBNFGF1IGF2MIFSLC6A8
ABCC3CD160CSF1RFGF2IL-13RA2MSl1SMO
ABL1CD19CSKFGF21IL-2mTORSOD1
ACE2CD22CTCFLFGFR1IL-2RANOS2Src
ADACD248CTGFFGFR2IL-3RANotch2SST
AhRCD27CTLA-4FGFR3IL-4Notch3STAT3
AKT1CD276CXCR1FGFR4IL-4RNOX3STAT6
AKT2CD28CXCR2FLT1IL-6PARP1Syk
AKT3CD33CXCR3FLT3IL-6RPARP2TAT
ALDH2CD37CXCR4FOXC2IL-8PARP3TBK1
ALKCD3eCXCR7FSHRIL-9RPCNATERT
ApoBCD4CYP17A1FynIRAK4PD1TF
ApoECD40CYP19A1GAS-6ITKPDE10ATGFB1
ARCD44CYP2A6GDF-2JAK1PDK1TLR3
ARL-1CD47DDR1GHRJAK2PECAM-1TLR4
ARVCFCD52DDR2GLP1RJAK3PIGFTLR5
ATF-5CD70DHFRGLSKAAG1Pim1TLR7
ATMCD74DHODHGnRH1KIR-2DL1Pim2TLR8
ATRAIDCD79BDKK1GnRH-RKIR-2DL2Pim3TLR9
AXLCD80DLL1GPRC5DKIR-2DL3PKMTNIK
Bcl2CD86DLL3GRB2KIR-3DL2PLK-1TP53
Bcl-2A1CD9DLL4GRP-RLAG-3PollTRPA1
BcrCDC7DNMT1GSTP1LCKPRAMETrpC5
BrafCDK1eEF1A-2GZMBLDLRPRF1TrpV1
BMP-10CDK2EGFHDAC1LRRK2PRLTRPV2
BMXCDK3EGFRHDAC2Ly-75PRL-RTSH-R
Brd2CDK4ENGHDAC3LYNPRMT5Tyk2
Brd3CDK5Ep-CAMHDAC6MAP3K9PROX-1UCH-L5
Brd4CDK6EphA2HDAC10MARCKSPTENUSP14
BTKCDK7EphA3HDAC11MC1-RPTK7VCAM-1
CACDK8EphB4HGFMCL1RAD51VCP
CA2CDK9EphB6HIF1AMDM2RanVDR
CA3CDK12ERBB2HK2Mdm4RETVIP
cAMPCDK19EZH2HPSEMECOMROBO4Wee1/2
CCKA-RCEACAM5FAP-αHSF1MELKROR1WNT5A
CCKB-RCEBPAFASHSPB1MerTKSEMA-4DWT1
CCR2CFTRFASLGIGF1METSHEXIAP

If you don't see the gene you are interested, please don't hesitate to contact us. CRISPR PlatformCB will provide you customized CRISPR/Cas9 gene editing services for your target genes. Tell us about your needs, we guarantee our clients the most reliable and efficient services to best match your research goals, with the shortest turnaround time and the most reasonable price.

For research use only. Not intended for any clinical use.

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