Key Targeted Gene Editing

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Key Targeted Gene Editing    

CRISPR/Cas9 gene editing technology brings a DNA editing revolution, which is faster, more accurate, less cost and has a wide range of potential applications than previous DNA editing techniques. Geneticists and medical researchers can use CRISPR/Cas9 technology to quickly delete, insert, or alter a portion of a DNA sequence. Guided by gRNA, Cas9 targets specific sites in the DNA and forms a double-stranded break (DSB). During DSB repair, one or more genetic changes are introduced through the non-homologous end joining (NHEJ) or homology directed repair (HDR, repair template required) pathway.

CRISPR PlatformCB, one of the leading gene editing technology companies, is specializing in CRISPR/Cas9 gene editing services. Based on our professional scientists' team and national-class labs, we have been successfully implemented hundreds of genes deletion in cells and mice using CRISPR/Cas9 technology (Table 1). We use optimized gene targeting strategies to achieve the most efficient gene editing efficiency, and we provide you with one-stop gene editing services, including designing gene editing strategies for the final cell line or model animal. To meet your research needs, we offer CRISPR/cas9 knockout, knock-in, point mutation, conditional knockout cell lines and animal models, etc.

Key Targeted Gene

ABCA1CCR4CLUFGFR1IL-3RANotch2SST
ABCC1CCR5CRBNFGFR2IL-4Notch3STAT3
ABCC3CD160CSF1RFGFR3IL-4RNOX3STAT6
ABL1CD19CSKFGFR4IL-6PARP1Syk
ACE2CD22CTCFLFLT1IL-6RPARP2TAT
ADACD248CTGFFLT3IL-8PARP3TBK1
AhRCD27CTLA-4FOXC2IL-9RPCNATERT
AKT1CD276CXCR1FSHRIRAK4PD1TF
AKT2CD28CXCR2FynITKPDE10ATGFB1
AKT3CD33CXCR3GAS-6JAK1PDK1TLR3
ALDH2CD37CXCR4GDF-2JAK2PECAM-1TLR4
ALKCD3eCXCR7GHRJAK3PIGFTLR5
ApoBCD4CYP17A1GLSKAAG1Pim1TLR7
ApoECD40CYP19A1GnRH1KIR-2DL1Pim2TLR8
ARCD44CYP2A6GnRH-RKIR-2DL2Pim3TLR9
ARL-1CD47DDR1GPRC5DKIR-2DL3PKMTNIK
ARVCFCD52DDR2GRB2KIR-3DL2PLK-1TP53
ATF-5CD70DHFRGRP-RLAG-3PollTRPA1
ATMCD74DHODHGSTP1LCKPRAMETrpC5
ATRAIDCD79BDKK1GZMBLDLRPRF1TrpV1
AXLCD80DLL1HDAC1LRRK2PRLTRPV2
Bcl2CD86DLL3HDAC2Ly-75PRL-RTSH-R
Bcl-2A1CD9DLL4HDAC3LYNPRMT5Tyk2
BcrCDC7DNMT1HDAC6MAP3K9PROX-1UCH-L5
BrafCDK1eEF1A-2HDAC10MARCKSPTENUSP14
BMP-10CDK2EGFHDAC11MC1-RPTK7VCAM-1
BMXCDK3EGFRHGFMCL1RAD51VCP
Brd2CDK4ENGHIF1AMDM2RanVDR
Brd3CDK5Ep-CAMHK2Mdm4RETVIP
Brd4CDK6EphA2HPSEMECOMROBO4Wee1/2
BTKCDK7EphA3HSF1MELKROR1WNT5A
CACDK8EphB4HSPB1MerTKSEMA-4DWT1
CA2CDK9EphB6IGF1METSHEXIAP
CA3CDK12EZH2IGF1RMGMTSLAMF7  
cAMPCDK19FASIGF2MIFSLC6A8  
CCKA-RCEACAM5FASLGIL-13RA2MSl1SMO  
CCKB-RCEBPAFGF1IL-2mTORSOD1  
CCR2CFTRFGF2IL-2RANOS2Src  

If you don't see the gene you are interested, please don't hesitate to contact us. CRISPR PlatformCB will provide you customized CRISPR/Cas9 gene editing services for your target genes. Tell us about your needs, we guarantee our clients the most reliable and efficient services to best match your research goals, with the shortest turnaround time and the most reasonable price.

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