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Homology repair (HDR) is a natural DNA repair mechanism induced by DNA double-strand breaks (DSB). The CRISPR/Cas9 system generates DSB on the chromosome, resulting in DNA repair. In the presence of donor DNA, homologous directed repair (HDR) occurs and replaces the genetic information (insertion, removal or substitution) in the chromosome with new information from the donor DNA.
CRISPR/Cas9 PlatformCB provides a competitive price for synthesizing donor DNA sequences, cloning them into your chosen vector and performing sequence verification, regardless of the size or complexity of the vector. Our expertise and experience in highly reliable CRISPR technology applications make us a valuable partner for researchers worldwide.
The strategy of HDR repair with donor vector is described as below
Workflow of custom CRISOR/Cas9 HDR vectors
You only need to provide
Expected turnaround time
CRISPR/Cas9 PlatformCB is dedicated to providing professional CRISPR/Cas9 gene editing services and products for biotechnology, biomedical research, and pharmaceutical research. We provide you with custom HDR vectors service from strategic design to final stable and efficient HDR vectors, and keep in touch with you to report on project progress. We guarantee the quality of our products and deliver them at the most reasonable price in the shortest turnaround time. We will meet your specific requirements to protect your scientific investment. If you have any question, please feel free to contact us.