Point Mutation Cell Line Generation


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Point Mutation Cell Line Generation    

CRISPR/Cas9 PlatformCB provides a point mutation cell line generation service for various cell lines, such as tumor cell lines and stem cell lines. As a provider of genome editing service, CRISPR/Cas9 PlatformCB focuses on using the latest technique to serve customers. With years of experience, our scientist team is expert in generating knock-in stable cell lines with CRISPR. At CRISPR/Cas9 PlatformCB, all projects are done by well-trained staff with excellent platform under the guide of talented scientists. We provide customers with reliable results and products.

Gene mutation is an important inducer for many diseases. With CRISPR/Cas9 system, it becomes possible to correct the mutated site in living cells. This technique is based on two factors, guide RNA and Cas9 nuclease. Guide RNA alters its sequence for different target sites, while Cas9 functions as a nuclease cutting double strand DNA. At the presence of template, homology directed repair pathway is activated for reconstructing the target site. Due to its versatility, CRISPR system is widely used all over the world and promotes the development of many research fields.


CRISPR/Cas9 PlatformCB offers a reliable cell line generation service of point mutation with CRISPR system. This service includes free consultation, cell line evaluation, sgRNA design and vector construction, homologous donor construction, cell transfection and selection, cell expansion and cryopreservation. Both pool cell and cell clone are available. We will work closely to you.


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Related Service:

  • Base Editing by CRISPR
  • Reporter Gene Knock-in Cell Line Generation
  • CISPR Off-Target Effects Analysis
  • Knockin Mouse Generation

For research use only. Not intended for any clinical use.