Custom CRISPR iPSC Services

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Custom CRISPR iPSC Services    

The availability and predictability of induced pluripotent stem cell (iPSC) technology provide new opportunities for drug discovery decisions. Induced pluripotent stem cells (iPSCs) derived from healthy patients or people with injuries or diseases provide an infinite, isogenic source of cell line models. iPSCs are capable of inducing differentiation into specific tissue lineages, providing a consistent source of physiologically relevant cell line models for research and screening purposes. With the help of the CRISPR/Cas9 gene editing, cell lines containing disease-associated mutations can be quickly created to reveal effects on function and phenotype. The combination of CRISPR/Cas9-mediated genetic modification and iPSC technology provides drug discovery researchers with a powerful tool for generating disease-specific models.

CRISPR PlatformCB, one of the leading gene editing biotechnology companies, is specializing in building efficient systems and procedures to meet the needs and timelines of clients working in the CRISPR/Cas9 gene editing. By combining our state-of-the-art iPSC production technology with CRISPR/Cas9 genome editing technology, we can provide high-precision CRISPR iPSC cell genome editing services that were previously difficult to provide. Tell us about the genes you are interested in., we will make full use of our unique expertise to help you complete your targeted gene knockout, knock-in, or point mutation in iPSC, and provide you with efficient and accurate genome editing services.

Various mutations can be designed

  • Conventional knockout (Gene destruction or site-specific large fragment knockout)
  • Conditional knockout/knockin
  • Point mutation
  • Report gene insertion
  • Rosa26 knockin

Our custom CRISPR iPSC services include but are not limited to

We guarantee three homozygous (or heterozygous) clones in which the modified line has the correct genetic mutation and three vials of each clone.

Why choose CRISPR/Cas9 PlatformCB?

  • Novel CRISPR strategy for higher efficiency and success rate (>98%)
  • Professional iPSC culture protocols
  • Rich experience: More than thousands of genetic editing project experience
  • Shorter turnaround time, lower price
  • Milestone update/report and final report
  • Isogenic control iPSC for reliable experiments
  • Comprehensive downstream iPSC differentiation and characterization services

Applications

  • Physiologically relevant disease models that are difficult to mimic disease (such as amyotrophic lateral sclerosis, muscular dystrophy, Parkinson's disease, Alzheimer's disease)
  • Different from using isogenic cell line models to study mutations in different tissue lineages
  • Suitable for targeted drug discovery, drug and toxicity screening

As a professional gene editing services company, CRISPR/Cas9 PlatformCB has successfully obtained >500 unique iPSC models with a success rate of > 98%, which have recognized by our customers. If you have any project need CRISPR/Cas9 iPSC, don’t hesitate to contact us. We will offer you a comprehensive custom CRISPR/Cas9 gene editing service from strategy design to final stable cell line, according to the gene you interest. We guarantee our clients the most reliable and efficient research services to best match your research goals.

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