Our promise to you:
Guaranteed product quality, expert customer support.
CRISPR/Cas9 PlatformCB offers you CRISPR-based gene knock-in rats at very competitive prices. those models are suitable for a variety of applications, including reporter gene expression, conditional gene expression, and disease models. We guarantee at least 2 founders or 3 F1 animals. Tell us the name of your gene and the target site you want to target; we will generate your rat model.
Our knock-in rats model includes
Consult our team of experts and tell us what genes and loci you want to knock in. We will customize high-efficiency targeting strategies for you, including the most suitable PAM sites, donor DNA and efficient gRNA sequences design, as well as genotyping primers design based on PCR and sequencing.
Synthesize gRNA, Cas9 mRNA, donor DNA, and construct CRISPR/Cas9 vector.
gRNA, Cas9 mRNA and donor DNA are simultaneously implanted into rat single-cell embryos (as many as possible).
Select the young rats with right gene editing by PCR and sequencing.
We will delivery at least 2 founders or 3 F1 rats, and final report which details each step, including target vector design, construction and validation, transfection conditions, genotyping strategies and results.
Applications of knock-in rats
|For academic research||For biopharmaceuticals research and development|
|Study the functions of specific genes/proteins||Human disease models (including genetic diseases, neurological diseases, cancer, etc.)|
|Study disease-causing transgene||Selectivity screening|
|Quantitative assessment of gene expression and protein localization||Drug screening and development|
|Study the role of transcriptional regulatory elements|
Our features and benefits
CRISPR/Cas9 PlatformCB is a leading biotechnology company focused on gene editing. We have extensive experience in processing animal embryos and have been very successful in integrating CRISPR/Cas9 technology into our procedures, which has been well received by customers. From the early strategic design to the final model, we guarantee to provide our customers with excellent service. Tell us the genes you are interested in and we will meet your specific requirements and protect your scientific investment.