PPIF Knockout Cell Line-293T

Cat.No.
CSC-RT0271
Description
293T-PPIF (-/-) is a stable cell line with a homozygous knockout of human PPIF
Host Cell
293T
Species
Human
Background
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. [provided by RefSeq, Jul 2008]

For research use only. Not intended for any clinical use.
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