DEK Knockout Cell Line-293T
Cat.No.
CSC-RT0285
Description
293T-DEK (-/-) is a stable cell line with a homozygous knockout of human DEK
Host Cell
293T
Species
Human
Background
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
For research use only. Not intended for any clinical use.
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