DCTPP1 Knockout Cell Line-293T

Cat.No.
CSC-RT0131
Description
293T-DCTPP1 (-/-) is a stable cell line with a homozygous knockout of human DCTPP1
Host Cell
293T
Species
Human
Background
The protein encoded by this gene is dCTP pyrophosphatase, which converts dCTP to dCMP and inorganic pyrophosphate. The encoded protein also displays weak activity against dTTP and dATP, but none against dGTP. This protein may be responsible for eliminating excess dCTP after DNA synthesis and may prevent overmethylation of CpG islands. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]

For research use only. Not intended for any clinical use.
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