ATG16L1 Knockout Cell Line-HeLa
Cat.No.
CSC-RT0141
Description
HeLa-ATG16L1 (-/-) is a stable cell line with a homozygous knockout of human ATG16L1
Host Cell
HeLa
Species
Human
Background
The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2010]
For research use only. Not intended for any clinical use.
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