Recombinant Human ROR1 (Frizzled domain, C-6His)

Name: Recombinant Human ROR1 (Frizzled domain, C-6His)
SKU: RP00104
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00104 Tag : C-6His

Expressed Region : Glu165-Asp305 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00104
Description	The Recombinant Human ROR1 (Frizzled domain, C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Glu165-Asp305 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol Weight	16.7 KDa
Format	Powder
Expressed Region	Glu165-Asp305
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	ROR1
Background	This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Synonyms	Inactive tyrosine-protein kinase transmembrane receptor ROR1; Neurotrophic tyrosine kinase, receptor-related 1; ROR1; NTRKR1

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