Human hTERT adenoviral particles

Name: Human hTERT adenoviral particles
SKU: AD00044Z
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : AD00044Z

Storage : -80℃ Shipping : Frozen on dry ice

Titer: Size:

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Virus Particles Information

Quality Control

Gene Information

Cat. No.	AD00044Z
Product Type	Adenoviral particle
Gene	TERT
Species	Human
Insert	hTERT
Titer	Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size	Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage	Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping	Frozen on dry ice

Summary	Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin	Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility	Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection	All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays	Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering	All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.

Gene Name	TERT telomerase reverse transcriptase [ Homo sapiens ]
Gene Symbol	TERT
Synonyms	TP2; TRT; EST2; TCS1; hTRT; DKCA2; DKCB4; hEST2; PFBMFT1
Gene Description	telomerase reverse transcriptase
GeneID	7015
Uni ProtID	O14746
mRNA Refseq	NM_198253.2
Protein Refseq	NP_937983.2
Chromosome Location	5p15.33
Function	metal ion binding; protein binding; protein homodimerization activity; telomerase activity; telomeric DNA binding; telomeric RNA binding; telomeric template RNA reverse transcriptase activity; telomeric template RNA reverse transcriptase activity;
Pathway	Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Extension of Telomeres, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; IL-2 Signaling Pathway, organism-specific biosystem;
MIM	187270

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