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Human EDNRB Stable Cell Line-U2OS

Cat.No.
CSC-RG0021
Abbr
U2OS-HuEDNRB
Alias
EDNRB,ABCDS,ET-B,ET-BR,ETB,ETBR,ETRB,HSCR,HSCR2,WS4A
Growth Properties
Adherent
Host Cell
U2OS
Morphology
Epithelial
Shipping
Dry ice
Species
Human
Background
The endothelins and their receptors are referred as the endothelin (ET) axis and this axis has been implicated in diverse tumours.
Endothelin B receptor (ETB) may oppose cancer advance by helping apoptosis and clearing ET-1; however, it has recently been involved in the progress of some tumour as melanomas or oligodendrogliomas. The multigenic disorder, Hirschsprung disease type 2, is due to mutation in endothelin receptor type B gene.

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