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Human EDNRB Stable Cell Line-CHO-K1

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Cat.No.
CSC-RG1730
Background
The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.
Host Cell
CHO-K1
Ship
Dry ice
Antigen Gene Information
Official Symbol
EDNRB
Synonyms
ETB; ET-B; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2
GeneID
MIM
UniProt ID
P24530
Chromosome Location
13q22
Pathway
Arf6 trafficking events, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Endothelin, organism-specific biosystem; Endothelins, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem;
Function
endothelin receptor activity; endothelin receptor activity; peptide hormone binding;

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