Human UTS2R Stable Cell Line-CHO-K1

Name: Human UTS2R Stable Cell Line-CHO-K1
SKU: CSC-RG0411
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RG0411

Host Cell : CHO-K1 Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RG0411
Background	The urotensin 2 receptor (UT or GPR14) is high affinity receptor for urotensin-2 and urotensin-2B. In human, Urotensin II is the most potent vasoconstrictor known, possibly contributing to several human cardiovascular diseases. Both UT receptor and urotensin II are widely expressed in many other tissues, implicating urotensin II in the pathogenesis of a variety of disease processes ranging from hypertension to hepatic cirrhosis and UT antagonists for the possibility of a new range of therapeutic drugs.
Target Gene	UTS2R
Gene Species	Homo sapiens (Human)
Abbr	CHO-HuUTS2R
Alias	UTS2R, GPR14, UTR, UTR2, UR-2-R
Host Cell	CHO-K1
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent
Morphology	Epithelial-like

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	UTS2R urotensin 2 receptor [ Homo sapiens ]
Gene Symbol	UTS2R
Synonyms	UTR; UTR2; GPR14; UR-2-R
Gene Description	urotensin 2 receptor
Gene ID	2837
Uni Prot ID	Q9UKP6
m RNA Refseq	NM_018949.1
Protein Refseq	NP_061822.1
Chromosome Location	17q25.3
Function	G-protein coupled receptor activity; urotensin II receptor activity;
Pathway	G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Gastrin-CREB signalling pathway via PKC and MAPK, organism-specific biosystem; Neuroactive ligand-receptor interaction, organism-specific biosystem; Neuroactive ligand-receptor interaction, conserved biosystem; Signal Transduction, organism-specific biosystem;
MIM	600896

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