Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDCR378432
| Cat. No. | CDCR378432 |
| Product Type | ORF Clone |
| Gene Abbr | Ednrb |
| Species | Rat |
| Tag | C-terminal Myc-DDK |
| ORF Size | 1329 bp |
| Vector | pCMV6-Entry |
| Target Gene | EDNRB |
| Background | The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Oct 2016] |
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