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Human ADCYAP1R1 Stable Cell Line-HEK293

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Cat.No.
CSC-RG0011
Background
Pituitary adenylate cyclase-activating polypeptide type I receptor, also known as PAC1 is a protein that in humans is encoded by the ADCYAP1R1 gene. ADCYAP1R1 is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor binds pituitary adenylate cyclase activating peptide (PACAP) mediating several biological activities and it is positively coupled to adenylate cyclase. ADCYAP1R1 is expressed in the adrenal medulla, pancreatic acini, uterus, myenteric plexus and brain.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
ADCYAP1R1
Synonyms
ADCYAP1R1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; pituitary adenylate cyclase-activating polypeptide type I receptor; PAC1; PAC1R; PACAP receptor 1; PACAPR; PACAP-R1; PACAP type I receptor; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop; PACAPRI;
Gene ID
MIM
UniProt ID
P41586
Chromosome Location
7
Pathway
Activation of TRKA receptors, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class B Secretin-like, organism-specific biosystem; Glucagon-type ligand receptors, organism-specific biosystem;
Function
ADP-ribosylation factor binding; adenylate cyclase binding; neuropeptide binding; pituitary adenylate cyclase-activating polypeptide receptor activity; receptor activity; signal transducer activity; vasoactive intestinal polypeptide receptor activity;

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