Human MC1R Stable Cell Line-CHO-K1

Name: Human MC1R Stable Cell Line-CHO-K1
SKU: CSC-RG0887
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RG0887

Host Cell : CHO-K1 Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RG0887
Background	The melanocortin 1 receptor is one of the key proteins in regulating hair and skin color. A member of the family of G-protein-coupled receptors, it functions at the surface of pigment producing cells (called melanocytes). After activation by MSH, the MC1 receptor is coupled to Gs signal pathway and is involved in many physical and pathological processes including skin pigmentation, autoimmune disease, inflammation and melanoma.
Target Gene	MC1R
Gene Species	Homo sapiens (Human)
Abbr	CHO-HuMC1R
Alias	MC1R, MSH R, MC1-R, CMM5, MSH-R, SHEP2, MGC14337
Host Cell	CHO-K1
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent
Morphology	Epithelial-like

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) [ Homo sapiens ]
Gene Symbol	MC1R
Synonyms	MC1R; melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor); melanocyte-stimulating hormone receptor; MSH R; MC1-R; melanotropin receptor; CMM5; MSH-R; SHEP2; MGC14337;
Gene ID	4157
Uni Prot ID	Q01726
m RNA Refseq	BC007856
Chromosome Location	16q24.3
Function	G-protein coupled peptide receptor activity; melanocortin receptor activity; melanocyte-stimulating hormone receptor activity; protein bind
Pathway	Chaperonin-mediated protein folding, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cooperation of Prefoldin and TriC/CCTin actin and tubulin folding, organism-specific biosystem; Diurnally regulated genes with circadian orthologs, organism-specific biosystem; Formation of tubulin folding intermediates by CCT/TriC, organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
MIM	155555

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