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Human MC1R Stable Cell Line-CHO-K1

Human MC1R Stable Cell Line-CHO-K1

Cat.No. :  CSC-RG0887 Host Cell:  CHO-K1

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Cell Line Information

Cell Culture Information

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Cat. No. CSC-RG0887
Background The melanocortin 1 receptor is one of the key proteins in regulating hair and skin color. A member of the family of G-protein-coupled receptors, it functions at the surface of pigment producing cells (called melanocytes). After activation by MSH, the MC1 receptor is coupled to Gs signal pathway and is involved in many physical and pathological processes including skin pigmentation, autoimmune disease, inflammation and melanoma.
Gene MC1R
Gene Species Homo sapiens (Human)
Alias MC1R, MSH R, MC1-R, CMM5, MSH-R, SHEP2, MGC14337
Host Cell CHO-K1
Host Cell Species Cricetulus griseus (Chinese hamster)
Morphology Epithelial-like
Stability Validated for at least 10 passages
Application

1. Gene expression studies

2. Signaling pathway research

3. Drug screening and toxicology

4. Research on the mechanisms of GPCR-related diseases

Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Shipping Dry ice
Storage Liquid nitrogen
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties Adherent
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations

The following safety precautions should be observed.

1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.

2. No eating, drinking or smoking while handling the stable line.

3. Wash hands after handling the stable line and before leaving the lab.

4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.

5. All waste should be considered hazardous.

6. Dispose of all liquid waste after each experiment and treat with bleach.

Ship Dry ice
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