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Human ADRA2B Stable Cell Line-CHO

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Cat.No.
CSC-RG0798
Background
Three alpha2-adrenoceptors have been cloned, and are designated alpha2A, alpha2B and alpha2C. All three receptors are activated by norepinephrine and all three are coupled via Gi to adenylate cyclase. The alpha2 adrenergic receptor is widely distributed in the CNS, lung, blood vessels and skeletal muscle and mediates vasoconstriction and modulation of neurotransmission.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Stability
12 passages of continuous culture (6 weeks at 2 passages/week)
Ship
Dry ice
Gene Information
Official Symbol
ADRA2B
Synonyms
ADRA2B; adrenergic, alpha-2B-, receptor; ADRA2L1, ADRA2RL1; alpha-2B adrenergic receptor; ADRARL1; alpha-2BAR; alpha-2B adrenoceptor; alpha-2B adrenoreceptor; G-protein coupled receptor; adrenergic receptor alpha 2B; alpha-2B-adrenergic receptor; alpha-2-adrenergic receptor-like 1; ADRA2B adrenergic, alpha-2B-, receptor; alpha-2 adrenergic receptor subtype C2; ADRA2L1; ADRA2RL1; ALPHA2BAR;
Gene ID
MIM
UniProt ID
P18089
Chromosome Location
2q11.1
Pathway
Adrenaline signalling through Alpha-2 adrenergic receptor, organism-specific biosystem; Adrenoceptors, organism-specific biosystem; Amine ligand-binding receptors, organism-specific biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (i) signalling events, organism-specific biosystem; G alpha (z) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem;
Function
G-protein coupled receptor activity; adrenergic receptor activity; alpha2-adrenergic receptor activity; epinephrine binding; protein binding; receptor activity; signal transducer activity;

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