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Rat Oprl1 Stable Cell Line-CHO dhfr-

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RG0348

Host Cell :   CHO dhfr- Size :   >1x106 frozen cells/vial

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Cell Culture Information

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Cat. No. CSC-RG0348
Background NOP, ORL1 or OPRL1 (opioid receptor-like 1 receptor) is also known as nociceptin receptor, orphanin FQ receptor and KOR-3 (kappa 3-related opioid receptor). It is a receptor for the neuropeptide nociceptin/orphanin FQ and has a potential role in modulating a number of brain functions, including instinctive behaviors and emotions. In vivo experiments have demonstrated that nociceptin modulates a variety of biological functions including nociception, food intake, memory processes, cardiovascular and renal functions, spontaneous locomotor activity, gastrointestinal motility, anxiety and neurotransmitter release at peripheral and central sites.
Target Gene Oprl1
Abbr CHO dhfr--RatOprl1
Alias OPRL1, ROR-C, KOR3, OFQR, ORL1, Oprl, XOR1, KOR-3, LC132, MOR-C
Host Cell CHO dhfr-
Host Cell Species Cricetulus griseus (Chinese hamster)
Applications

1. Gene expression studies

2. Signaling pathway research

3. Drug screening and toxicology

4. Research on the mechanisms of GPCR-related diseases

Size >1x106 frozen cells/vial
Stability Validated for at least 10 passages
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid nitrogen
Shipping Dry ice
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties Adherent
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
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