Human TRPV4 Stable Cell Line-CHO

Name: Human TRPV4 Stable Cell Line-CHO
SKU: CSC-RI0203
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RI0203

Host Cell : CHO Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RI0203
Description	This cell line is engineered to overexpress human TRPV4.
Background	The human TRPV4 gene encodes the pore-forming subunit of TRPV4, a moderately selective (PCa/PNa = 6) cation channel. TRPV4 channels are therapeutic targets in pain and asthma.
Target Gene	TRPV4
Gene Species	Homo sapiens (Human)
Abbr	CHO-HuTRPV4
Alias	TRPV4, CMT2C, OTRPC4, TRP12, VR OAC, VRL 2, VROAC, VRL2, SPSMA, HMSN2C, SSQTL1
Host Cell	CHO
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Channelopathies research
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TRPV4 transient receptor potential cation channel, subfamily V, member 4 [ Homo sapiens ]
Gene Symbol	TRPV4
Synonyms	TRPV4; transient receptor potential cation channel, subfamily V, member 4; transient receptor potential cation channel subfamily V member 4; CMT2C; osmosensitive transient receptor potential channel 4; OTRPC4; TRP12; VR OAC; VRL 2; VROAC; osm-9-like TRP channel 4; vanilloid receptor-like channel 2; transient receptor potential protein 12; OSM9-like transient receptor potential channel 4; vanilloid receptor-related osmotically activated channel; VRL2; SPSMA; HMSN2C; SSQTL1;
GeneID	59341
Uni ProtID	Q9HBA0
mRNA Refseq	BC117426
Chromosome Location	12q24.1
Function	SH2 domain binding; actin binding; actin filament binding; alpha-tubulin binding; beta-tubulin binding; calcium channel activity; calmodulin binding; cation channel activity; microtubule binding; protein kinase C binding; protein kinase binding;
MIM	605427

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