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Human TACR1-tGFP Stable Cell Line-SHSY5Y

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Cat.No.
CSC-RG0035
Background
Neurokinin 1 receptor gene encodes the receptor for the tachykinin substance P, also referred to as Neurokinin 1. Neurokinin receptors family is a group of Gcoupled proteins whose principal ligands are Neurokinins. The NK1 receptor is localized in high concentrations in the CNS and it is thought to mediate central stress reactions, mood control, excitatory neurotransmission, etc. The binding of SP (Substance P) to the receptor seems to be implicated in the transmission of stress signals and pain.
Growth Properties
Mixed, adherent and suspension
Morphology
Epithelial
Host Cell
SHSY5Y
Ship
Dry ice
Gene Information
Official Symbol
TACR1
Synonyms
TACR1; tachykinin receptor 1; TAC1R; substance-P receptor; NK1R; NKIR; SPR; NK-1R; NK-1 receptor; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor);
Gene ID
MIM
UniProt ID
P25103
Chromosome Location
2p13.1-p12
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Measles, organism-specific biosystem;
Function
G-protein coupled receptor activity; protein binding; receptor activity; signal transducer activity; substance P receptor activity; tachykinin receptor activity;

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