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Human TACR1 Stable Cell Line-HEK293

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Cat.No.
CSC-RG0017
Background
Tachykinin receptor 1 (TACR1) also known as neurokinin 1 receptor (NK1R) or substance P receptor (SPR) belongs to a family of proteins characterized by the interaction with G proteins. TACR1 is localized both in the central nervous system (CNS) and peripheral tissues. Tachykinin receptor 1 presents great affinity for Substance P agonist. This receptor is an interesting drug target in the studies about analgesics and antidepressants.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
TACR1
Synonyms
TACR1; tachykinin receptor 1; TAC1R; substance-P receptor; NK1R; NKIR; SPR; NK-1R; NK-1 receptor; tachykinin receptor 1 (substance P receptor; neurokinin-1 receptor);
Gene ID
MIM
UniProt ID
P25103
Chromosome Location
2p13.1-p12
Pathway
Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; Measles, organism-specific biosystem;
Function
G-protein coupled receptor activity; protein binding; receptor activity; signal transducer activity; substance P receptor activity; tachykinin receptor activity;

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