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Human SCN9A Stable Cell Line-CHO

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Cat.No.
CSC-RI0170
Background
The human SCN9A gene encodes the pore-forming subunit of Nav1.7, a voltage-gated sodium channel. Mutations in SCN9A channels have been linked to several inherited diseases including erythromelalgia (vasodilation with burning pain), paroxysmal extreme pain disorder, and congenital indifference to pain). Nav1.7, upregulated in prostatic cancer and inflammation, is a cancer biomarker and a therapeutic target in treatment of pain.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO
Ship
Dry ice
Gene Information
Official Symbol
SCN9A
Synonyms
SCN9A; sodium channel, voltage-gated, type IX, alpha subunit; sodium channel, voltage gated, type IX, alpha polypeptide; sodium channel protein type 9 subunit alpha; ETHA; Nav1.7; NE NA; NENA; PN1; hNE-Na; peripheral sodium channel 1; neuroendocrine sodium channel; sodium channel protein type IX subunit alpha; voltage-gated sodium channel alpha subunit Nav1.7; voltage-gated sodium channel subunit alpha Nav1.7; sodium channel, voltage-gated, type IX, alpha polypeptide; SFNP; FEB3B; NE-NA; GEFSP7;
Gene ID
MIM
UniProt ID
Q15858
Chromosome Location
2q24
Pathway
Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Interaction between L1 and Ankyrins, organism-specific biosystem; L1CAM interactions, organism-specific biosystem;
Function
voltage-gated ion channel activity; voltage-gated sodium channel activity;

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