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Human SCN1A Stable Cell Line-HEK293

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Cat.No.
CSC-RI0047
Background
The voltage gated sodium channel isoform Nav1.1 is involved with axon potential initiation and repetitive neuronal firing as well as the contraction-excitation coupling of cardiac myocytes. Nav1.1 is the target of antiepileptic drugs and the probable target causing side effects of centrally active local anaesthetics. It is detected cardiac myocytes as well as in the cell bodies of central neurons.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
SCN1A
Synonyms
FEB3; FHM3; NAC1; SCN1; SMEI; EIEE6; FEB3A; HBSCI; GEFSP2; Nav1.1; sodium channel protein type 1 subunit alpha; sodium channel protein type 1 subunit alpha; voltage-gated sodium channel type I; sodium channel protein type I subunit alpha; sodium channel protein brain I subunit alpha; sodium channel protein, brain I alpha subunit; sodium channel voltage gated type 1 alpha subunit; voltage-gated sodium channel subunit alpha Nav1.1; sodium channel, voltage-gated, type I, alpha polypeptide
Gene ID
MIM
UniProt ID
P35498
Chromosome Location
2q24.3
Pathway
Axon guidance; Developmental Biology; Dopaminergic synapse; Interaction between L1 and Ankyrins; L1CAM interactions; Adult walking behavior; Neuromuscular process controlling posture;
Function
Sodium ion binding; Voltage-gated sodium channel activity

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