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Human SCN10A/SCN3B Stable Cell Line-CHO

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Cat.No.
CSC-RI0172
Background
The human Nav1.8 gene encodes the pore-forming subunit of a voltage-gated Na+ channel that is expressed in nociceptive peripheral neurons. Co-expression with the auxiliary beta 3 subunit promotes surface expression. The Nav1.8 channel is a therapeutic target in pain treatment.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO
Ship
Dry ice
Gene Information
Official Symbol
SCN3B
Synonyms
SCN3B; HSA243396; SCNB3; sodium channel, voltage-gated, type III, beta subunit; sodium channel subunit beta-3; voltage-gated sodium channel beta-3 subunit
Gene ID
MIM
UniProt ID
Q9NY72
Chromosome Location
11q23.3
Pathway
Axon guidance; Developmental Biology; Direct p53 effectors; Interaction between L1 and Ankyrins; L1CAM interactions
Function
ion channel binding; sodium channel regulator activity; voltage-gated sodium channel activity; voltage-gated sodium channel activity involved in regulation of cardiac muscle cell action potential

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