Human SCN3B Nanodisc

Name: Human SCN3B Nanodisc
SKU: OE-PNDC000335
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : OE-PNDC000335

Tag : C-Flag tag and Strep Tag Expression System : Mammalian expression system

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Product Information

Gene Information

Cat. No.	OE-PNDC000335
Description	Human SCN3B nanodisc contains full length human SCN3B protein that is produced from HEK293 cells. Our nanodisc platform employs the mammalian expression system, which ensures that the Human SCN3B protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications, while maintaining exceptional solubility and stability. This nanodisc is an optimal tool for investigating the Human SCN3B membrane protein.
Gene Abbr	SCN3B
Gene Name	SCN3B
Species	Human
Gene Species	Human
Tag	C-Flag tag and Strep Tag
Features	1) Full-length membrane protein 2) Utilizing a mammalian expression system to ensure that the protein closely resembles its native counterpart in terms of structure, function, and post-translational modifications 3) Maintaining the native spatial conformation and activity of the membrane protein 4) Possessing high solubility and stability 5) High purity determined by HPLC 6) No detergents need to be added in subsequent experiments, and it can be directly applied to cytological analysis
Applications	1) Studying protein structure and function: Understanding the structure and activity of membrane proteins in a native-like environment. 2) Studying protein-protein and protein-ligand interactions: Analyzing how membrane proteins interact with other molecules, such as antibodies or other proteins. 3) Drug discovery: Identifying and characterizing potential drug candidates that target membrane proteins. 4) Developing antibodies: Screening and characterizing antibodies that bind to membrane proteins.
Format	Lyophilized protein
Expression System	Mammalian expression system
Note	For Research Use Only.
Storage	Store at -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within one month, aliquot and store at -80°C. Repeated freeze-thaw cycles should be avoided.
Shipping	Lyophilized proteins are shipped under ambient temperature conditions.

Target Gene

SCN3B

Background

Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel beta subunit gene family, and influences the inactivation kinetics of the sodium channel. Two alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]

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