Recombinant Human PD-1 (C-6His)

Name: Recombinant Human PD-1 (C-6His)
SKU: RP00356

Cat.No. : RP00356 Tag: C-6His

Expressed Region: Pro21-Gln167 Expression System: Human Cell

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Product Details

Target Information

Cat. No.	RP00356
Description	The Recombinant Human PD-1 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Pro21-Gln167 with a 6His tag at the C terminus.
Species	Human
Tag	C-6His
Mol. Weight	17 KDa
Expressed Region	Pro21-Gln167
Expression System	Human Cell
Format	Powder
Formulation	Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Trehalose, 100mM NaCl, 0.05% Tween 80, pH 7.5.
Conjugate	Unconjugated
Endotoxin Level	< 1 EU/µg of protein by LAL method
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	PD1
Background	Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
Synonyms	Programmed cell death protein 1; hPD-1; PDCD1; CD279

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