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Human PDCD1 Stable Cell Line-CHO

Cat.No.
CSC-RO0069
Description
This cell line is a stably transfected cell line which expresses human programmed cell death 1 (PDCD1).
Host Cell
CHO-K1
Shipping
Dry ice
Source
CHO-K1
Species
Human
Target
Human
Background
PDCD1 protein is a cell surface membrane protein of the immunoglobulin superfamily. It is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
Gene Information
Gene Symbol
PDCD1
Synonyms
PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1
Gene ID
UniProt ID
Q15116
Chromosome Location
2q37.3

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