Human PDCD1 Stable Cell Line-CHO-K1

Name: Human PDCD1 Stable Cell Line-CHO-K1
SKU: CSC-RO0069

For research use only. Not intended for any clinical use.

Cat.No.

CSC-RO0069

Description

This cell line is a stably transfected cell line which expresses human programmed cell death 1 (PDCD1).

Background

PDCD1 protein is a cell surface membrane protein of the immunoglobulin superfamily. It is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Host Cell

CHO-K1

Quality Control

Negative for bacteria, yeast, fungi and mycoplasma.

Shipping

Dry ice

Source

CHO-K1

Stability

Validated for at least 10 passages

Storage

Liquid nitrogen

Target

Human

Publications

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