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Rat Pdcd1 ORF Clone(NM_001106927.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR373704

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Product Information

Gene Information

Cat. No. CDCR373704
Product Type ORF Clone
Gene Abbr Pdcd1
Species Rat
Tag C-terminal Myc-DDK
ORF Size 864 bp
Vector pCMV6-Entry
Target Gene PDCD1
Background Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
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