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Recombinant Mouse SNCA (N-6His)

For research use only. Not intended for any clinical use.

Cat. No. :   RP00224 Tag :   N-6His

Expressed Region :   Met1-Ala140 Expression System :   E.coli

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Product Information

Gene Information

Cat. No. RP00224
Description The Recombinant Mouse SNCA (N-6His) is produced in our E.coli expression system. The amino acid region expressed is Met1-Ala140 with a 6His tag at the N terminus.
Species Mouse
Tag N-6His
Mol Weight 15.9 KDa
Conjugate Unconjugated
Format Powder
Expressed Region Met1-Ala140
Expression System E.coli
Formulation Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Purity >95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
Endotoxin Level < 1 EU/µg of protein by LAL method
Storage Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Target Gene Snca
Background Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Synonyms Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP; Snca
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