Recombinant Cynomolgus PD-1 (C-6His)

Name: Recombinant Cynomolgus PD-1 (C-6His)
SKU: RP00332
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00332 Tag : C-6His

Expressed Region : Pro21-Gln167 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00332
Description	The Recombinant Cynomolgus PD-1 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Pro21-Gln167 with a 6His tag at the C terminus.
Species	Cynomolgus
Tag	C-6His
Mol Weight	17.3 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Pro21-Gln167
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	PD1
Background	Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
Synonyms	Programmed cell death 1; PD-1; PD1

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