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Human PTGFR Stable Cell Line-HEK293

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Cat.No.
CSC-RG1716
Background
The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene.
Host Cell
HEK293
Ship
Dry Ice
Antigen Gene Information
Official Symbol
PTGFR
Synonyms
PTGFR; FP; prostaglandin F receptor (FP); RP5-944H6.1; PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; prostaglandin F2 alpha receptor; prostaglandin F2-alpha receptor; prostaglandin receptor (2-alpha); prostanoid FP receptor
GeneID
MIM
UniProt ID
P43088
Chromosome Location
1p31.1
Pathway
Calcium signaling pathway; Class A/1 (Rhodopsin-like receptors); Eicosanoid ligand-binding receptors; GPCR downstream signaling; GPCR ligand binding; GPCRs, Class A Rhodopsin-like; Gastrin-CREB signalling pathway via PKC and MAPK
Function
prostaglandin F receptor activity

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