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Human PTGFR Validated Stable Cell Line-CHO

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Cat.No.
CSC-RG1206
Background
Prostaglandin F (2-alpha) is involved in a number of physiologic processes. It serves as a potent luteolytic agent in many species, has been implicated as a modulator of intraocular pressure, smooth muscle contraction in the uterus and elsewhere. Its effects on cells are mediated through specific interaction with the prostaglandin F receptor (FP or PTGFR). Knockout mice lacking the FP
receptor are unable to deliver normal fetuses at term due to a lack of response to oxytocin. The mice also failed to show the decline in serum progesterone expected to precede parturition.
Growth Properties
Adherent
Morphology
Epithelial-like
Host Cell
CHO-K1
Ship
Dry ice
Gene Information
Official Symbol
PTGFR
Synonyms
PTGFR; FP; prostaglandin F receptor (FP); RP5-944H6.1; PGF receptor; PGF2 alpha receptor; PGF2-alpha receptor; prostaglandin F2 alpha receptor; prostaglandin F2-alpha receptor; prostaglandin receptor (2-alpha); prostanoid FP receptor
Gene ID
MIM
UniProt ID
P43088
Chromosome Location
1p31.1
Pathway
Calcium signaling pathway; Class A/1 (Rhodopsin-like receptors); Eicosanoid ligand-binding receptors; GPCR downstream signaling; GPCR ligand binding; GPCRs, Class A Rhodopsin-like; Gastrin-CREB signalling pathway via PKC and MAPK
Function
prostaglandin F receptor activity

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