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Human KCNA5 Stable Cell Line-HEK293

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Cat.No.
CSC-RI0131
Background
The human KCNA5 gene encodes the pore-forming subunit of Kv1.5, a voltage-gated potassium channel. A KCNA5 mutation has been linked to an inherited form of atrial fibrillation. Kv1.5 channels are widely expressed in heart, colon, kidney, vascular smooth muscle and CNS, and are therapeutic targets in atrial fibrillation, pulmonary hypertension, cancer, and multiple sclerosis.
Growth Properties
Adherent
Morphology
Epithelial
Host Cell
HEK293
Ship
Dry ice
Gene Information
Official Symbol
KCNA5
Synonyms
KCNA5; potassium voltage-gated channel, shaker-related subfamily, member 5; potassium voltage-gated channel subfamily A member 5; HK2; HPCN1; Kv1.5; potassium channel 1; cardiac potassium channel; potassium channel protein; voltage-gated potassium channel HK2; insulinoma and islet potassium channel; voltage-gated potassium channel protein Kv1.5; voltage-gated potassium channel subunit Kv1.5; HCK1; PCN1; ATFB7; KV1.5; MGC117058; MGC117059;
Gene ID
MIM
UniProt ID
P22460
Chromosome Location
12p13
Pathway
Neuronal System, organism-specific biosystem; Potassium Channels, organism-specific biosystem; Voltage gated Potassium channels, organism-specific biosystem;
Function
delayed rectifier potassium channel activity; outward rectifier potassium channel activity; potassium channel inhibitor activity; receptor binding; voltage-gated ion channel activity;

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