Cat.No. : CSC-RG1745 Host Cell: HeLa
| Cat. No. | CSC-RG1745 |
| Background | Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. |
| Gene | F2RL1 |
| Gene Species | Homo sapiens (Human) |
| Host Cell | HeLa |
| Species | Homo sapiens (Human) |
| Stability | Validated for at least 10 passages |
| Application | 1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases |
| Quality Control | Negative for bacteria, yeast, fungi and mycoplasma. |
| Shipping | Dry ice |
| Storage | Liquid nitrogen |
| Source | HeLa |
| Subgroup | Human |
| Revival | Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media. |
| Gene Name | F2RL1 coagulation factor II (thrombin) receptor-like 1 [ Homo sapiens ] |
| Gene Symbol | F2RL1 |
| Synonyms | PAR2; GPR11 |
| Gene ID | 2150 |
| UniProt ID | P55085 |
| mRNA Refseq | BC018130 |
| Chromosome Location | 5q13 |
| Function | G-protein alpha-subunit binding;G-protein beta-subunit binding;G-protein coupled receptor activity;G-protein coupled receptor activity;protein binding; |
| Pathway | African trypanosomiasis, organism-specific biosystem;African trypanosomiasis, conserved biosystem;Class A/1 (Rhodopsin-like receptors), organism-specific biosystem;G alpha (q) signalling events, organism-specific biosystem;GPCR downstream signaling, organism-specific biosystem;GPCR ligand binding, organism-specific biosystem;GPCRs, Class A Rhodopsin-like, organism-specific biosystem; |
| MIM | 600933 |
| Mycoplasma | Negative |
| Format | One frozen vial containing millions of cells |
| Storage | Liquid nitrogen |
| Safety Considerations |
The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach. |
| Ship | Dry ice |
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.
Our promise to you:
Guaranteed product quality, expert customer support.
24x7 CUSTOMER SERVICE
CONTACT US TO ORDER
Copyright © Creative Biogene. All rights reserved.
