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Human F2RL1 Stable Cell Line-HeLa

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Cat.No.
CSC-RG1745
Background
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor.
Host Cell
HeLa
Ship
Dry ice
Antigen Gene Information
Official Symbol
F2RL1
Synonyms
PAR2; GPR11
GeneID
MIM
UniProt ID
P55085
Chromosome Location
5q13
Pathway
African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem;
Function
G-protein alpha-subunit binding; G-protein beta-subunit binding; G-protein coupled receptor activity; G-protein coupled receptor activity; protein binding; receptor activity; receptor binding; thrombin receptor activity;

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