Recombinant Mouse GPC3 (C-6His)

Name: Recombinant Mouse GPC3 (C-6His)
SKU: RP00267
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : RP00267 Tag : C-6His

Expressed Region : Gln25-Met557 Expression System : Human Cell

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Product Information

Gene Information

Cat. No.	RP00267
Description	The Recombinant Mouse GPC3 (C-6His) is produced in our Human Cell expression system. The amino acid region expressed is Gln25-Met557 with a 6His tag at the C terminus.
Species	Mouse
Tag	C-6His
Mol Weight	61.6 KDa
Conjugate	Unconjugated
Format	Powder
Expressed Region	Gln25-Met557
Expression System	Human Cell
Formulation	Lyophilized from a 0.2 μm filtered solution of PBS, 5% Trehalose, pH 7.4.
Purity	>95% as determined by SDS-PAGE. >90% as determined by SEC-MALS.
Endotoxin Level	< 1 EU/µg of protein by LAL method
Storage	Upon receipt, this product is stable for up to 6 months at temperatures below -70°C. Once reconstituted, the product is stable for up to 1 week at 4°C and up to 3 months at -20°C. Please avoid repeated freeze-thaw cycles.
Shipping	The product is shipped with ice packs. Upon receipt, store it immediately at the temperature recommended below.
Reconstitution	Always centrifuge tubes before opening. It is recommended to reconstitute the solution to a concentration above 100 μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Target Gene	Gpc3
Synonyms	Glypican-3; GTR2-2; Intestinal protein OCI-5; MXR7; GPC3; OCI5

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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

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