Mouse GPC3 ORF clone(NM_016697.3)

Name: Mouse GPC3 ORF clone(NM_016697.3)
SKU: CDCL184449
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL184449

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Product Information

Gene Information

Cat. No.	CDCL184449
Description	ORF Clone of Mus musculus glypican 3 DNA.
Product Type	ORF clone
Gene Abbr	GPC3
Species	Mouse
ORF Size	1740bp
Vector	pGEM-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

GPC3

Background

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

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