Mouse Gpc3 Insect Cell Lysate

Name: Mouse Gpc3 Insect Cell Lysate
SKU: CLOE-2357
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CLOE-2357 Host Cell : Baculovirus-Insect cell

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Cell Lysate Information

Gene Information

Cat. No.	CLOE-2357
Introduction	This cell lysate over-expresses mouse Gpc3 (NP_057906.2) (Met1-Pro558) fused with C-terminal his tag. Purification of target protein (s) from this cell lysate has been verified.
Target Gene	Gpc3
Host Cell	Baculovirus-Insect cell
Applications	Positive control for Western Blot (WB), antibody verification, protein purification
Storage	Upon receipt, store at 4°C, or prepare aliquots and store at -80°C. Multiple freeze-thaw cycles should be avoided.
Shipping	Ice package

Target Gene

GPC3

Background

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

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