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Rat EDNRA Stable Cell Line-CHO-K1

For research use only. Not intended for any clinical use.

Cat. No. :   CSC-RG1729

Host Cell :   CHO-K1 Size :   >1x106 frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No. CSC-RG1729
Background This gene encodes a protein that exhibits endothelin receptor activity. The receptor binds endothelin 1 and induces an increase in intracellular calcium.
Target Gene EDNRA
Host Cell CHO-K1
Host Cell Species Cricetulus griseus (Chinese hamster)
Source CHO-K1
Applications

1. Gene expression studies

2. Signaling pathway research

3. Drug screening and toxicology

4. Research on the mechanisms of GPCR-related diseases

Size >1x106 frozen cells/vial
Stability Validated for at least 10 passages
Quality Control Negative for bacteria, yeast, fungi and mycoplasma.
Storage Liquid nitrogen
Shipping Dry ice
Revival Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Mycoplasma Negative
Format One frozen vial containing millions of cells
Storage Liquid nitrogen
Safety Considerations The following safety precautions should be observed.
1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum.
2. No eating, drinking or smoking while handling the stable line.
3. Wash hands after handling the stable line and before leaving the lab.
4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells.
5. All waste should be considered hazardous.
6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship Dry ice
Gene Name Ednra endothelin receptor type A [ Rattus norvegicus ]
Gene Symbol Ednra
Synonyms Eta; ET-A; ET-AR; Endor; RGD1559432
Gene Description endothelin receptor type A
Gene ID 24326
Uni Prot ID A1Y2B8
m RNA Refseq NM_012550.2
Protein Refseq NP_036682.1
Chromosome Location 19q11
Function endothelin receptor activity; endothelin receptor activity; endothelin receptor activity; endothelin receptor activity;
Pathway Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem;
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