Human TRPM4 Stable Cell Line-CHO

Name: Human TRPM4 Stable Cell Line-CHO
SKU: CSC-RI0196
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-RI0196

Host Cell : CHO Size : >1x10⁶ frozen cells/vial

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Cell Line Information

Cell Culture Information

Safety and Packaging

Gene Information

Cat. No.	CSC-RI0196
Description	This cell line is engineered to overexpress human TRPM4.
Background	The human TRPM4 gene encodes the pore-forming subunit of TRPM4, a non-selective, cation-permeable channel expressed in lymphocytes, heart, vascular smooth muscle, intestine, and prostate. A gain-of-function mutation in TRPM4 is associated with progressive familial heart block type I. TRPM4 channels are therapeutic targets in inflammation and immune disorders.
Target Gene	TRPM4
Gene Species	Homo sapiens (Human)
Abbr	CHO-HuTRPM4
Alias	TRPM4, FLJ20041, LTrpC4, hTRPM4, PFHB1B, TRPM4B
Host Cell	CHO
Host Cell Species	Cricetulus griseus (Chinese hamster)
Applications	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Channelopathies research
Size	>1x10⁶ frozen cells/vial
Stability	Validated for at least 10 passages
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid nitrogen
Shipping	Dry ice

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm2 flask containing pre-warmed media.
Growth Properties	Adherent

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	TRPM4 transient receptor potential cation channel, subfamily M, member 4 [ Homo sapiens ]
Gene Symbol	TRPM4
Synonyms	TRPM4; transient receptor potential cation channel, subfamily M, member 4; transient receptor potential cation channel subfamily M member 4; FLJ20041; LTrpC4; hTRPM4; melastatin-4; long transient receptor potential channel 4; calcium-activated non-selective cation channel 1; PFHB1B; TRPM4B;
GeneID	54795
Uni ProtID	Q8TD43
mRNA Refseq	BC132727
Chromosome Location	19q13.3
Function	ATP binding; calcium activated cation channel activity; calcium channel activity; calmodulin binding; ion channel activity; nucleotide binding;
MIM	606936

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