Human P2RY12 Stable Cell Line-1321N1

Name: Human P2RY12 Stable Cell Line-1321N1
SKU: CSC-RG0374

Cat.No. : CSC-RG0374 Host Cell: 1321N1

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Cell Line Information

Cell Culture Information

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Cat. No.	CSC-RG0374
Background	P2RY12 or P2Y12 is a G-protein coupled receptor for ADP and ATP. ADT released from platelets acts in a positive feedback mechanism on P2Y12 and P2Y1 on platelets and is critical for sustained aggregation and stabilization of thrombin. P2Y12 receptor plays a central role in platelet activation and is the target of of antithrombotic drugs such as ticlopidine and clopidogrel.
Gene	P2RY12
Gene Species	Homo sapiens (Human)
Alias	P2RY12, HORK3, P2Y12, SP1999, ADPG-R, BDPLT8, P2T(AC), P2Y(AC), P2Y(ADP), P2Y(cyc)
Host Cell	1321N1
Host Cell Species	Homo sapiens (Human)
Morphology	Glial
Stability	Validated for at least 10 passages
Application	1. Gene expression studies 2. Signaling pathway research 3. Drug screening and toxicology 4. Research on the mechanisms of GPCR-related diseases
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Shipping	Dry ice
Storage	Liquid nitrogen

Revival	Rapidly thaw cells in a 37°C water bath. Transfer contents into a tube containing pre-warmed media. Centrifuge cells and seed into a 25 cm² flask containing pre-warmed media.
Growth Properties	Adherent

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

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